
Hi-Tech Quercetin
Hi-Tech Pharmaceuticals has once again taken an excellent ingredient and utilized our Cyclosome® delivery to make it considerably better. Hi-Tech’s goal was to overcome the low bioavailability hurdle of Quercetin and Hi-Tech achieved that with the novel delivery system Cyclosome® to boost absorption.
Hi-Tech used a more soluble formulation of Quercetin based on phosphatidylcholine and beta cyclodextrin. Quercetin Cyclosome, has recently been developed, and was found to facilitate the attainment of very high plasma levels of Quercetin—up to 20 times more than usually obtained following a dose of Quercetin—when the novel formulation was administered orally in human volunteers. These results suggest that Quercetin Cyclosome allows the oral administration of Quercetin in a safe and bioavailable manner, thus facilitating the effective utilization of this natural compound to help boost natural immunity.
Quercetin’s antiviral capacity has been attributed to four main mechanisms of action:
Quercetin is a flavonoid found naturally in a number of foods including apples, onions, teas, berries, and red wine. Quercetin has been shown to encourage a healthy immune response, especially to seasonally changing environments. In addition, Quercetin acts as an antioxidant, neutralizing free radicals—the chemical by-products that harm cell membranes and damage DNA while possessing significant antihistamine and anti-inflammatory properties.
Quercetin's best-known mechanism of action involves its ability to stabilize mast cell membranes, which in turn can decrease the release of histamine. In this way it provides nutritional support for individuals who occasionally suffer from allergies. A number of Quercetin's beneficial effects appear to be due to its antioxidant activity. Quercetin also encourages healthy nitric oxide levels, which helps maintain already healthy blood pressure levels. This bioflavonoid also supports healthy cholesterol levels already within normal range.
Lastly, and more importantly, since March 2020 Quercetin has been a first line of defense towards Immune Health. Liaquat University of Medical & Health Sciences has begun a study to show just how effective this compound is when complexed with phosphatidylcholine. Severe infections are believed to be triggered by an over-reaction of the immune system, known as a "cytokine storm" that result in hyperinflammation throughout the body, including the lungs, heart and brain. The cytokine storm exacerbates the person's breathing difficulties and can lead to potentially deadly results.
Quercetin, a flavonoid, is a known modulator of inflammatory response with strong anti-inflammatory capacities including: modulation of NF-kB transcription factor, inhibition of cytokines (e.g. TNF-α), inhibition of production of pro-inflammatory enzymes, such as cyclooxygenase (COX) and lipoxygenase (LOX), which catalyze the conversion of arachidonic acid to its metabolites. The combination of three crucial properties of Quercetin as antioxidant, anti-inflammatory and immunomodulatory makes it a potential candidate to support all unhealthy conditions where oxidative stress, inflammation and immunity are involved. The investigators in the study at Liaquat University of Medical & Health Sciences believe that the bioavailable form of Quercetin (Quercetin complexed with phosphatidylcholine ) can prevent the "cytokine storm", which would be a revolutionary breakthrough in Immune Health unlike anything before it in the natural realm
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